CARDIZEM SR 120mg Tablet

CARDIZEM SR 120mg Tablet

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CARDIZEM SR 120MG TABLET

Description & Uses

  • Active Ingredient: Diltiazem Hydrochloride (120mg) in a sustained-release (SR) formulation.
  • What it does: It is a non-dihydropyridine calcium channel blocker. The sustained-release mechanism allows for a gradual and even release of diltiazem, helping to dilate blood vessels, improve oxygen supply to the heart muscle, and control heart rate smoothly throughout the day.
  • Prescribed for: Long-term prevention and management of chronic stable or vasospastic chest pain (angina pectoris), treatment of mild-to-moderate high blood pressure (essential hypertension), and prevention of certain fast heart rhythms (supraventricular tachyarrhythmias).

Dosage & Administration

  • Standard Regimen: Typically 120mg taken twice daily (every 12 hours) in divided doses. Dose adjustments are made based on response up to a typical daily maximum of 360mg (elderly up to 240mg daily).
  • Important Rules: Take your doses at the same times every day to maintain stable blood levels. It can be taken with or without food.
  • Strict Administration Rule: Swallow the tablet whole. Do not crush, chew, or split it, as doing so destroys the sustained-release matrix, causing a rapid and dangerous release of the entire dose into your system.
  • Do Not Stop Abruptly: Never stop taking this medication suddenly, particularly if you are treating angina. Abruptly halting can cause a rebound of severe chest pain or a dangerous blood pressure spike.
  • Dietary Warning: Do not drink grapefruit juice while on this medication. Grapefruit raises the concentration of diltiazem in your blood, which can lead to severe side effects.

Contraindications & Warnings

  • When NOT to use: Do not take this medication if you have a very slow heart rate (bradycardia), sick sinus syndrome, second- or third-degree AV block (without a functioning pacemaker), severe low blood pressure (systolic under 90 mmHg), acute heart failure, or fluid in the lungs (pulmonary congestion).
  • Interactions: Avoid taking this medicine with other drugs that slow your heart rate or affect cardiac conduction (such as beta-blockers, amiodarone, or digoxin) without close doctor supervision. It can also increase the blood levels of certain cholesterol-lowering statins (like atorvastatin or simvastatin).

Side Effects

  • Headache, dizziness, fatigue, and sudden flushing or warmth in the face.
  • Swelling of the ankles or lower legs (peripheral edema).
  • Nausea, constipation, or mild indigestion.
  • Warning Signs: Contact your healthcare provider immediately if you experience a dangerously slow heartbeat, severe dizziness, fainting, or swelling that rapidly worsens.

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