Active Ingredient: Diltiazem Hydrochloride (30mg).
What it does: It is a non-dihydropyridine calcium channel blocker. It works by inhibiting the influx of calcium ions into cardiac and vascular smooth muscle cells. This relaxes and dilates the blood vessels (lowering blood pressure) and slows electrical conduction in the heart, reducing heart rate and workload.
Prescribed for: Prevention of chronic stable chest pain (angina pectoris), angina due to coronary artery spasms (Prinzmetal's angina), mild-to-moderate high blood pressure (hypertension), and control of certain abnormal, rapid heart rhythms (arrhythmias).
Standard Regimen: Typically 30mg taken 3 to 4 times daily before meals and at bedtime. Your doctor may gradually increase this dose every 1 to 2 days based on your response, up to a typical maximum of 180mg to 300mg per day.
Important Rules: Take your doses at evenly spaced intervals throughout the day. Unlike the extended-release (CD/LA) formulations, standard Cardizem 30mg immediate-release tablets can be split or crushed if directed by your doctor, though they are usually swallowed whole with water.
Do Not Stop Abruptly: If you are taking this for angina, never stop taking this medication suddenly.
Dietary Warning: Avoid drinking grapefruit juice or eating grapefruit while on this medication.
Common: Swelling of the ankles or lower legs (edema), headache, dizziness, sudden facial flushing, nausea, or constipation.
Contraindications: Do not take this medication if you have a very slow heart rate (bradycardia), severe low blood pressure (systolic below 90 mmHg), advanced heart block (unless you have a working pacemaker), or fluid buildup in the lungs (pulmonary congestion).
Critical Interactions: Exercise extreme caution if taking this alongside beta-blockers (like Metoprolol) or digitalis (Digoxin), as the combination can lead to severe slowing of the heart rate or conduction block.